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Its combination with first-line platinum-based chemotherapy was evaluated in a phase I/II trial
These provide the most objective assessment of both efficacy and side effect burden
At equimolar doses, this novel compound, GIC-1001 (trimebutine 3-thiocarbamoylbenzene-sulphonate), shows rapid onset of action (2 h) and more effectively mitigates nociceptive responses to colorectal distension, providing pain relief during colonoscopy (Table 4)
Papi A, Contoli M, Gasparini P, Bristot L, Edwards MR, Chicca M, et al
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